Performance of Ethanolic Extracts from Tagetes patula Flowers on Antioxidants and Against Skin Aging-Related Enzymes
Keywords:
French marigold, anti-aging, antioxidant, ethanolic extractAbstract
Plant extracts have been used for skin care is an alternative choice to reduce skin aging. The aims of this study were to investigate the performance of ethanolic extracts from flowers of 10 cultivars of French marigolds including KPS01-SY, KPS02-SO, KPS03-SO, KPS04-DO, KPS05-DY, KPS06-SR, KPS07-SY, KPS08-DO, KPS09-DY and KPS10-DR at concentration of 100 µg/mL as antioxidants and anti-aging. The results showed that ethanolic extracts from 10 French marigolds gave inhibitory capacity on DPPH· more than 80%. Three cultivars, KPS04-DO, KPS06-SR and KPS08-DO gave good inhibitory effect on ABTS·, however, the result was not significantly different from that of BHT (84.57%). While, the extracts from 10 cultivars of French marigolds had a few effects on inhibition of NO· and LDL oxidation, range from 2.20-17.91%. In case of aging-related enzymes inhibition, the ethanolic extract of KPS01-SY showed highest inhibitory effect on collagenase and hyaluronidase enzymes (57.92 and 48.44%, respectively), as compared to other extracts. The ethanolic extract of KPS08-DO showed better inhibitory activities on elastase, hyaluronidase and tyrosinase (51.07, 49.30 and 14.25%, respectively) than those of other cultivars. However, ethanolic extracts of KPS01-SY and KPS08-DO had weaker inhibitory activities against collagenase, elastase, hyaluronidase than oleanolic acid. The extracts also showed weaker inhibitory activities against tyrosinase than kojic acid. As the results, ethanolic extracts from flowers of KPS08-DO could be used a source of bioactive compounds as antioxidant and against skin aging-related enzymes.
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